Abstract: The success of artificial oral infection to Anguilla japonica Temminck et Schlegel by Edwardsiella fujianensis Han et a confirmed that the infection was induced through digestive tract by the bacteria,Several histopathological observations indicatedtbat the germs dissolved the liver cells into focal necrosis and caused hyperplasiaof hematopoietic tissue of kidney.The focal necrosis changed into abscess whensecondary infection happened with Aeromonas,which is the reason for eel deathand different symptomes of Edwardsielliasis for liver type of kidney type.