Abstract: History-We have recently found what is probably the earliest record of Ichthyophthi- riasis, under the Chinese common name of "white spot or fish-louse disease", in a book edited by Su-shih (苏轼) sometime during the Sung Dynasty (A. D. 964-1126), which has the modern-sounding title "Inter-relationships of Organisms". The then popular remedy for this discase affecting cultivated fishes was the leaves of Acer tree. We have not had the opportunity of testing this since these trees are not yet in leaf.