Abstract: The representative biomimetic sampling technology is the triolein-filled semi-permeable membrane device(SPMD), in which hydrophobic organic pollutants could be accumulated in the similar way as that in fish. In the study, SPMD and goldfish(Crassius auratus)were simultaneously exposed to nine weakly hydrophobic nitroaromatics in a laboratory continuous-flow experimental system. Our results showed that the accumulation of the nitroaromatics in SPMD and in fish was compared and good correlation between device concentration factor and the octanol/water distribution coefficients of the compounds. When exposing to the same concentration, the difference between device concentration factor and bioconcentration factor represents the characteristics of the enzymatic degradation of nitroaromatics in goldfish.