鱼类垂体腺苷酸环化酶激活多肽的研究进展
ADVANCES IN THE RESEARCH OF PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE IN FISH
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摘要: 垂体腺苷酸环化酶激活多肽 (Pituitary adenylate cyclasea ctivating polypeptide, PACAP)是 1989年首次在绵羊下丘脑发现的具有广泛生物活性的多肽,是促胰液素 /胰高血糖素家族新成员[1]。
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关键词:
- 鱼类 /
- 垂体腺苷酸环化酶激活多肽 /
- 下丘脑促垂体激素 /
- 生长激素 /
- 促性腺激素
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Keywords:
- Fish /
- PACAP /
- Hypophysiotropic hormone /
- Growth hormone /
- Gonadotropin
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[1] Arimura A. Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine and nervous systems[J]. Japanese Journal of Physiology, 1998,48:301-331[2] Vinczo E, Koves K. Structure, localization and physiologic role of pituitary adenylate cyclase activating polypeptide (PACAP) [J].Orv. Hetil,2001,142(10):491-496[3] Wong A O, Li W S, Lee E K, et al. Pituitary adenylate cyclase activating polypeptide as a novel hypophysiotropic factor in fish[J]. Biochem. Cell. Biol., 2000, 78(3):329-343[4] Delgado E, Wei Y, Martin S C, et al. Cloning and characterization of PACAP peptides in zebrafish[R]. Program and abstracts, 10th International Congress of Endocrinology; 1996; June 12-16, San Francisco[5] Matsuda K, Takel Y, Katoh J, et al. Isolation and structural characterization of pituitary adenylate cyclase activating polypeptide (PACAP)-like peptide the brain of a teleost,stargazer, Uranoscopus japonicus[J]. Peptides, 1997, 18:723-727[6] Parker D B, Coe I R, Dison G H, et al. Two salmon neuropeptides encoded by one brain cDNA are structurally related to members of the glucagon superfamily[J]. Eur. J. Biochem., 1993, 215:439-448[7] Parker D B, Power M E, Swanson P, et al. Exon skipping in the gene encoding pituitary adenylate cyclase activating polypeptide in salmon alters the expression of two hormones that stimulate growth hormone release[J]. Endocrinology, 1997, 138:414-423[8] Kwon H B, Joss J M P, Ishii S. Recent Progress in Molecular and Comparative Endocrinology[M]. Chonnam:HRC Press. 1999. 383-388[9] McRory J E, Parker D B, Ngamvongchon S, et al. Sequence and expression of cDNA for Pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH)-like peptide in catfish[J]. Mol. Cell. Endocrinol., 1995, 1085:167-177[10] Fradinger E A, Sherwood N M. Characterization of the gene encoding both growth hormone-releasing hormone(GRF) and pituitary adenylate cyclase-activating polypeptide (PACAP) in the zebrafish[J]. Mol. Cell. Endocrinol., 2000, 165(1-2):211-219[11] Krueckl S L, Sherwood N M. Developmental expression, alternative splicing and gene copy number for the pituitary adenylate cyclase-activating polypeptide(PACAP) and growth hormone-releasing hormone (GRF) gene in rainbow trout [J]. Mol. Cell Endocrinol., 2001,182(1):99-108[12] Small B C, Nonneman D. Sequence and expression of a cDNA encoding both pituitary adenylate cyclase activating polypeptide and growth hormone-releasing hormone-like peptide in channel catfish (Ictalurus punctatus) [J] Gen. Comp. Endocrinol., 2001, 122(3):354-363[13]Montero M, Yon L, Kikuyama S, et al. Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family: Functional implication in the regulation of growth hormone secretion[J]. J. Mol. Endocrinol., 2000, 25(2):157-168[14] Wray V, Nokihara K, Naruse S. Solution structure comparsion of the VIP/PACAP family of peptides by NMR spectroscopy[J]. Ann. NY Acad. Sci., 1998, 865:37-44[15] Chartrel N, Tonon M. C, Vaudry H, et al. Primary structure of frog pituitary adenylate cyclase activating polypeptide (PACAP) and effects of ovine PACAP on frog pituitary[J]. Endocrinology, 1991,129:3367-3371[16] Yasuhara T, Mizuno K, Somogyvari-Vigh A, et al. Isolation and primary structure of chicken PACAP[J]. Regul, pept., 1992, 37: 326[17] Matsuda K, Yoshida T, Nagano Y. et al. Purification and primary structure of pituitary adenylate cyclase activating polypeptide (PACAP) from the brain of an elasmobranch, stingray,Dasyatis akajei[J].Peptides, 1998, 19(9):1489-1495[18] Sherwood N M, Hew C L. Fish physiology, Vol. , Molecular Endocrinology of Fish [M]. New York: Academic Press. 1994.3-66[19] McRory J, Sherwood N M. Two protochordate genes encode pituitary adenylate cyclase activating polypeptide and related family members[J]. Endocrinology, 1997, 138:2380-2390[20] McRory J E, Parker R L, Sherwood NM. Expression and altemative processing of a chicken gene encoding both growth hormone-releasing hormone and pituitary adenylate cyclase-activating polypeptide[J]. DNA Cell Biol., 1997, 16(1):95-102[21] Montero M, Yon L, Rousseau K, et al. Distribution, characterization, and growth hormone releasing activity of pituitary adenylate cyclase activating polypeptide (PACAP) in the European eel, Anguilla anguilla[J]. Endocrinology, 1998, 139:4300-4310[22] Wong A O L, Leung M Y, Shea W L C, et al. Hypophysiotropic Action of pituitary adenylate cyclase activating polypeptide (PACAP) in the goldfish: immunohistochemical demonstration of PACAP in the pituitary, PACAP stimulation of growth hormone release from pituitary cells, and molecular cloning of pituitary type I PACAP Receptor[J]. Endocrinology, 1998, 139:3465-3479[23] Matsuda K, Shioda S, Arimura A, et al. The study of pituitary adenylate cyclase activating polypeptide (PACAP)-like immunoreactivity in the brain of a teleost, stargazer, Uranoscopus japonicus[J]. Zool. Sci., 1997, 14:645-650[24] Matsuda K, Itoh Y, Yoshida T, et al. The localization of pituitary adenylate cyclase activating polypeptide (PACAP)-like immunoreactivity in the hypothalamo-pituitary region of an elasmobranch, stingray, Dasyatis akajei[J]. Peptides, 1998, 19(7):1263-1267[25] Jonsson AC. Galanin-, VIP-, and PACAP-like nerves in the Brockmann body of the cod Gadus morhua and the rainbow trout Oncorhynchus mykiss innervate the insulin-and glucagons-containing cells[J]. Neth.J.Zool., 1995,45:132-134[26] Olsson C, Holmgren S. The control of gut motility[J]. Comp. Biochem. Physiol. A Mol. Integr. Physiol., 2001, 128(3):479-501[27] De Girolamo P, Arcamone N, Rosica A, et al. PACAP (pituitary adenylate cyclase activating polypeptide)-like immunoreactivity in the gill arch of the goldfish, Carassius auratus: distribution and comparison with VIP[J]. Cell. Tissue. Res.,1998, 293(3):567-571[28] Reid S G, Fritsche R, Jonsson AC Immunohistochemical localization of bioactive peptides and amines associated with the chromaffin tissue of five species of fish[J]. Cell. Tissue. Res., 1995, 280(3):499-512[29] Montpetit C J, Perry S F. Vasoactive intestinal polypeptide- and pituitary adenylate cyclase activating polypeptide-mediated control of catecholamine release from chromaffin tissue in the rainbow trout,Oncorhynchus mykiss[J]. J.Endocrinol.,2000, 166(3):705-714[30] Matsudaa K, Kashimoto K, Higuchi T, et al. Presence of pituitary adenylate cyclase-activating polypeptide (PACAP) and its relaxant activity in the rectum of a teleost, the stargazer, Uranoscopus japonicus[J].Peptides, 2000, 21(6):821-827[31] Wei Y, Martin S C, Heinrich G, et al. Cloning and functional characterization of PACAP-specific receptors in zebrafish[J]. Ann. N Y Acad. Sci., 1998, 865:45-48[32] Chow B K C, Yuen T T H, Chan K W. Molecular evolution of vertebrate VIP receptors and functional characterization of a VIP receptor from goldfish, Carassius auratus[J].Gen. Comp. Endocrinol.,1997, 105:176-185[33] Chow B K C. The goldfish vasoactive intestinal polypeptide receptor: Functional studies and tissue distribution[J]. Fish. Physiol. Biochem.,1997, 17:213-222[34] Xiao D, Chu M M, Lee E K, et al. Regulation of growth hormone release in common carp pituitary cells by pituitary adenylate cyclase-activating polypeptide: Signal transduction involves cAMP-and calcium-dependent mechanisms[J].Neuroendocrinology, 2002,76(5):325-338[35] Rousseau K, Le Belle N, Pichavant K, et al. Pituitary growth hormone secretion in the turbot, a phylogenetically recent teleost, is regulated by a species-specific pattern of neuropeptides [J].Neuroendocrinology, 2001, 74(6):375-385[36] Xiao D, Chu M M, Lee E K, et al. Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on intracellular cAMP and Ca2+ levels in common carp (Cyprinus carpio) pituitary cells in vitro [J]. Acta Biochimica et Biophysica Sinica,2002,34(60):790-795.[肖东,朱美诗,李继仁,等. 垂体腺苷酸环化酶激活多肽对鲤鱼脑垂体细胞内cAMP和胞内Ca2+的影响.生物化学与生物物理学报,2002,34(6):790-795][37] Chang JP, Wirachowsky NR, Kwong P, et al. PACAP stimulation of gonadotropin-Ⅱ secretion in goldfish pituitary cells: mechanisms of action and interaction with gonadotropin releasing hormone signaling [J]. J. Neuroendocrinol., 2001, 13(6):540-550[38]Gur G, Bonfil D, Safarian H, et al. Pituitary adenylate cyclase activating polypeptide and neuropeptide Y regulation of gonadotropin subunit gene expression in tilapia: role of PKC, PKA and ERK[J]. Neuroendocrinology. 2002, 75(3):164-174 Arimura A. Perspectives on pituitary adenylate cyclase activating polypeptide (PACAP) in the neuroendocrine, endocrine and nervous systems[J]. Japanese Journal of Physiology, 1998,48:301-331[2] Vinczo E, Koves K. Structure, localization and physiologic role of pituitary adenylate cyclase activating polypeptide (PACAP) [J].Orv. Hetil,2001,142(10):491-496[3] Wong A O, Li W S, Lee E K, et al. Pituitary adenylate cyclase activating polypeptide as a novel hypophysiotropic factor in fish[J]. Biochem. Cell. Biol., 2000, 78(3):329-343[4] Delgado E, Wei Y, Martin S C, et al. Cloning and characterization of PACAP peptides in zebrafish[R]. Program and abstracts, 10th International Congress of Endocrinology; 1996; June 12-16, San Francisco[5] Matsuda K, Takel Y, Katoh J, et al. Isolation and structural characterization of pituitary adenylate cyclase activating polypeptide (PACAP)-like peptide the brain of a teleost,stargazer, Uranoscopus japonicus[J]. Peptides, 1997, 18:723-727[6] Parker D B, Coe I R, Dison G H, et al. Two salmon neuropeptides encoded by one brain cDNA are structurally related to members of the glucagon superfamily[J]. Eur. J. Biochem., 1993, 215:439-448[7] Parker D B, Power M E, Swanson P, et al. Exon skipping in the gene encoding pituitary adenylate cyclase activating polypeptide in salmon alters the expression of two hormones that stimulate growth hormone release[J]. Endocrinology, 1997, 138:414-423[8] Kwon H B, Joss J M P, Ishii S. Recent Progress in Molecular and Comparative Endocrinology[M]. Chonnam:HRC Press. 1999. 383-388[9] McRory J E, Parker D B, Ngamvongchon S, et al. Sequence and expression of cDNA for Pituitary adenylate cyclase activating polypeptide (PACAP) and growth hormone-releasing hormone (GHRH)-like peptide in catfish[J]. Mol. Cell. Endocrinol., 1995, 1085:167-177[10] Fradinger E A, Sherwood N M. Characterization of the gene encoding both growth hormone-releasing hormone(GRF) and pituitary adenylate cyclase-activating polypeptide (PACAP) in the zebrafish[J]. Mol. Cell. Endocrinol., 2000, 165(1-2):211-219[11] Krueckl S L, Sherwood N M. Developmental expression, alternative splicing and gene copy number for the pituitary adenylate cyclase-activating polypeptide(PACAP) and growth hormone-releasing hormone (GRF) gene in rainbow trout [J]. Mol. Cell Endocrinol., 2001,182(1):99-108[12] Small B C, Nonneman D. Sequence and expression of a cDNA encoding both pituitary adenylate cyclase activating polypeptide and growth hormone-releasing hormone-like peptide in channel catfish (Ictalurus punctatus) [J] Gen. Comp. Endocrinol., 2001, 122(3):354-363[13]Montero M, Yon L, Kikuyama S, et al. Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family: Functional implication in the regulation of growth hormone secretion[J]. J. Mol. Endocrinol., 2000, 25(2):157-168[14] Wray V, Nokihara K, Naruse S. Solution structure comparsion of the VIP/PACAP family of peptides by NMR spectroscopy[J]. Ann. NY Acad. Sci., 1998, 865:37-44[15] Chartrel N, Tonon M. C, Vaudry H, et al. Primary structure of frog pituitary adenylate cyclase activating polypeptide (PACAP) and effects of ovine PACAP on frog pituitary[J]. Endocrinology, 1991,129:3367-3371[16] Yasuhara T, Mizuno K, Somogyvari-Vigh A, et al. Isolation and primary structure of chicken PACAP[J]. Regul, pept., 1992, 37: 326[17] Matsuda K, Yoshida T, Nagano Y. et al. Purification and primary structure of pituitary adenylate cyclase activating polypeptide (PACAP) from the brain of an elasmobranch, stingray,Dasyatis akajei[J].Peptides, 1998, 19(9):1489-1495[18] Sherwood N M, Hew C L. Fish physiology, Vol. , Molecular Endocrinology of Fish [M]. New York: Academic Press. 1994.3-66[19] McRory J, Sherwood N M. Two protochordate genes encode pituitary adenylate cyclase activating polypeptide and related family members[J]. Endocrinology, 1997, 138:2380-2390[20] McRory J E, Parker R L, Sherwood NM. Expression and altemative processing of a chicken gene encoding both growth hormone-releasing hormone and pituitary adenylate cyclase-activating polypeptide[J]. DNA Cell Biol., 1997, 16(1):95-102[21] Montero M, Yon L, Rousseau K, et al. Distribution, characterization, and growth hormone releasing activity of pituitary adenylate cyclase activating polypeptide (PACAP) in the European eel, Anguilla anguilla[J]. Endocrinology, 1998, 139:4300-4310[22] Wong A O L, Leung M Y, Shea W L C, et al. Hypophysiotropic Action of pituitary adenylate cyclase activating polypeptide (PACAP) in the goldfish: immunohistochemical demonstration of PACAP in the pituitary, PACAP stimulation of growth hormone release from pituitary cells, and molecular cloning of pituitary type I PACAP Receptor[J]. Endocrinology, 1998, 139:3465-3479[23] Matsuda K, Shioda S, Arimura A, et al. The study of pituitary adenylate cyclase activating polypeptide (PACAP)-like immunoreactivity in the brain of a teleost, stargazer, Uranoscopus japonicus[J]. Zool. Sci., 1997, 14:645-650[24] Matsuda K, Itoh Y, Yoshida T, et al. The localization of pituitary adenylate cyclase activating polypeptide (PACAP)-like immunoreactivity in the hypothalamo-pituitary region of an elasmobranch, stingray, Dasyatis akajei[J]. Peptides, 1998, 19(7):1263-1267[25] Jonsson AC. Galanin-, VIP-, and PACAP-like nerves in the Brockmann body of the cod Gadus morhua and the rainbow trout Oncorhynchus mykiss innervate the insulin-and glucagons-containing cells[J]. Neth.J.Zool., 1995,45:132-134[26] Olsson C, Holmgren S. The control of gut motility[J]. Comp. Biochem. Physiol. A Mol. Integr. Physiol., 2001, 128(3):479-501[27] De Girolamo P, Arcamone N, Rosica A, et al. PACAP (pituitary adenylate cyclase activating polypeptide)-like immunoreactivity in the gill arch of the goldfish, Carassius auratus: distribution and comparison with VIP[J]. Cell. Tissue. Res.,1998, 293(3):567-571[28] Reid S G, Fritsche R, Jonsson AC Immunohistochemical localization of bioactive peptides and amines associated with the chromaffin tissue of five species of fish[J]. Cell. Tissue. Res., 1995, 280(3):499-512[29] Montpetit C J, Perry S F. Vasoactive intestinal polypeptide- and pituitary adenylate cyclase activating polypeptide-mediated control of catecholamine release from chromaffin tissue in the rainbow trout,Oncorhynchus mykiss[J]. J.Endocrinol.,2000, 166(3):705-714[30] Matsudaa K, Kashimoto K, Higuchi T, et al. Presence of pituitary adenylate cyclase-activating polypeptide (PACAP) and its relaxant activity in the rectum of a teleost, the stargazer, Uranoscopus japonicus[J].Peptides, 2000, 21(6):821-827[31] Wei Y, Martin S C, Heinrich G, et al. Cloning and functional characterization of PACAP-specific receptors in zebrafish[J]. Ann. N Y Acad. Sci., 1998, 865:45-48[32] Chow B K C, Yuen T T H, Chan K W. Molecular evolution of vertebrate VIP receptors and functional characterization of a VIP receptor from goldfish, Carassius auratus[J].Gen. Comp. Endocrinol.,1997, 105:176-185[33] Chow B K C. The goldfish vasoactive intestinal polypeptide receptor: Functional studies and tissue distribution[J]. Fish. Physiol. Biochem.,1997, 17:213-222[34] Xiao D, Chu M M, Lee E K, et al. Regulation of growth hormone release in common carp pituitary cells by pituitary adenylate cyclase-activating polypeptide: Signal transduction involves cAMP-and calcium-dependent mechanisms[J].Neuroendocrinology, 2002,76(5):325-338[35] Rousseau K, Le Belle N, Pichavant K, et al. Pituitary growth hormone secretion in the turbot, a phylogenetically recent teleost, is regulated by a species-specific pattern of neuropeptides [J].Neuroendocrinology, 2001, 74(6):375-385[36] Xiao D, Chu M M, Lee E K, et al. Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on intracellular cAMP and Ca2+ levels in common carp (Cyprinus carpio) pituitary cells in vitro [J]. Acta Biochimica et Biophysica Sinica,2002,34(60):790-795.[肖东,朱美诗,李继仁,等. 垂体腺苷酸环化酶激活多肽对鲤鱼脑垂体细胞内cAMP和胞内Ca2+的影响.生物化学与生物物理学报,2002,34(6):790-795][37] Chang JP, Wirachowsky NR, Kwong P, et al. PACAP stimulation of gonadotropin-Ⅱ secretion in goldfish pituitary cells: mechanisms of action and interaction with gonadotropin releasing hormone signaling [J]. J. Neuroendocrinol., 2001, 13(6):540-550[38]Gur G, Bonfil D, Safarian H, et al. Pituitary adenylate cyclase activating polypeptide and neuropeptide Y regulation of gonadotropin subunit gene expression in tilapia: role of PKC, PKA and ERK[J]. Neuroendocrinology. 2002, 75(3):164-174
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